rs886039484
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We suggest that SNPs in the P53 pathway, especially the P21 ser31arg polymorphism and combined polymorphisms especially the P21/ MDM2 might be genetic susceptibility factors in the pathogenesis of AML.
|
23167335 |
2012 |
rs1057520001
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We suggest that SNPs in the P53 pathway, especially the P21 ser31arg polymorphism and combined polymorphisms especially the P21/ MDM2 might be genetic susceptibility factors in the pathogenesis of AML.
|
23167335 |
2012 |
rs1057519975
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We previously identified a case of human acute myelogenous leukemia (AML) in which both alleles of the p53 gene had undergone independent missense mutations (at codons 135 cys to ser and 246 met to val).
|
1918170 |
1991 |
rs483352695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We previously identified a case of human acute myelogenous leukemia (AML) in which both alleles of the p53 gene had undergone independent missense mutations (at codons 135 cys to ser and 246 met to val).
|
1918170 |
1991 |
rs121912651
|
|
|
0.710 |
GeneticVariation |
BEFREE |
We have recently established the MV4-11 acute myelogenous leukemia (AML) subline, designated as MV4-11 TP53 R248W, which possesses a missense mutation (CGG→TGG; R248W) in the TP53 gene, leading to inactivation of this transcription factor.
|
21550660 |
2011 |
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There is no significant association of P53 arg72pro polymorphism on the risk of AML.
|
23167335 |
2012 |
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There is no significant association of P53 arg72pro polymorphism on the risk of AML.
|
23167335 |
2012 |
rs878854066
|
|
|
0.020 |
GeneticVariation |
BEFREE |
There is no significant association of P53 arg72pro polymorphism on the risk of AML.
|
23167335 |
2012 |
rs587782529
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The novel somatic mutation, R337G (16900C>G), was discovered in myelodysplastic syndrome with transformation to acute myeloblastic leukemia, developing as the third primary in the LFS child.
|
19714490 |
2009 |
rs121912651
|
|
A |
0.710 |
GeneticVariation |
CLINVAR |
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
|
25157968 |
2014 |
rs11540652
|
|
T |
0.710 |
GeneticVariation |
CLINVAR |
Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.
|
24641375 |
2014 |
rs1057519747
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.
|
24641375 |
2014 |
rs121912666
|
|
C |
0.700 |
GeneticVariation |
CLINVAR |
Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.
|
24641375 |
2014 |
rs121913343
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.
|
24641375 |
2014 |
rs28934576
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.
|
24641375 |
2014 |
rs587782329
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.
|
24641375 |
2014 |
rs121912651
|
|
A |
0.710 |
GeneticVariation |
CLINVAR |
p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells.
|
20013323 |
2010 |
rs11540652
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells.
|
30948782 |
2019 |
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the results suggest that there is no association between TP53 Arg72Pro polymorphism and the risk of leukemia, but the CC genotype may increase the risk of ALL TP53 Arg72Pro polymorphism CC genotype may increase the risk of ALL but is not associated with AML.
|
27053289 |
2016 |
rs1131691014
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the results suggest that there is no association between TP53 Arg72Pro polymorphism and the risk of leukemia, but the CC genotype may increase the risk of ALL TP53 Arg72Pro polymorphism CC genotype may increase the risk of ALL but is not associated with AML.
|
27053289 |
2016 |
rs878854066
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, the results suggest that there is no association between TP53 Arg72Pro polymorphism and the risk of leukemia, but the CC genotype may increase the risk of ALL TP53 Arg72Pro polymorphism CC genotype may increase the risk of ALL but is not associated with AML.
|
27053289 |
2016 |
rs11540652
|
|
A |
0.710 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
rs11540652
|
|
G |
0.710 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
rs11540652
|
|
T |
0.710 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |
rs121912651
|
|
C |
0.710 |
GeneticVariation |
CLINVAR |
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
|
26619011 |
2016 |